Oncotarget

VOLUME 7 (2016)

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About The Cover

Sixth BHD symposium and first international upstate kidney cancer symposium: latest scientific and clinical discoveries. See Bratslavsky et al.

Table of Contents

Editorial

Synapsin III in brain development

https://doi.org/10.18632/oncotarget.8106
15288-15289
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Editorial: Gerotarget (Focus on Aging)

TGFβ1Smad signaling pathways are not required for epidermal LC homeostasis

https://doi.org/10.18632/oncotarget.8167
15290-15291
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Meeting Reports

Sixth BHD Symposium and First International Upstate Kidney Cancer Symposium: latest scientific and clinical discoveries

https://doi.org/10.18632/oncotarget.7733
15292-15298
Abstract  |  PDF  |  Full Text  |  How to cite  |  Press Release

Priority Research Papers

Divergent branches of mitochondrial signaling regulate specific genes and the viability of specialized cell types of differentiated yeast colonies

https://doi.org/10.18632/oncotarget.8084
15299-15314
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Multiple genetic imaging study of the association between cholesterol metabolism and brain functional alterations in individuals with risk factors for Alzheimer’s disease

https://doi.org/10.18632/oncotarget.8100
15315-15328
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Pathology

Altered expression of neuropeptide Y receptors caused by focal cortical dysplasia in human intractable epilepsy

https://doi.org/10.18632/oncotarget.7855
15329-15338
Abstract  |  PDF  |  Full Text  |  How to cite

Deinococcus radiodurans pprI expression enhances the radioresistance of eukaryotes

https://doi.org/10.18632/oncotarget.8137
15339-15355
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Immunology

Exosomes released by granulocytic myeloidderived suppressor cells attenuate DSSinduced colitis in mice

https://doi.org/10.18632/oncotarget.7324
15356-15368
Abstract  |  PDF  |  Full Text  |  How to cite

Downregulation of the stressinduced ligand ULBP1 following SV40 infection confers viral evasion from NK cell cytotoxicity

https://doi.org/10.18632/oncotarget.8085
15369-15381
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CCR5 knockout suppresses experimental autoimmune encephalomyelitis in C57BL/6 mice

https://doi.org/10.18632/oncotarget.8097
15382-15393
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Protein phosphatase Mg2+/Mn2+dependent 1A controls the innate antiviral and antibacterial response of macrophages during HIV1 and Mycobacterium tuberculosis infection

https://doi.org/10.18632/oncotarget.8190
15394-15409
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reviews: Gerotarget (Focus on Aging)

Reprogramming of energy metabolism as a driver of aging

https://doi.org/10.18632/oncotarget.7645
15410-15420
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews: Immunology

Improving the clinical impact of biomaterials in cancer immunotherapy

https://doi.org/10.18632/oncotarget.7304
15421-15443
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

Tumor resistance to vascular disrupting agents: mechanisms imaging and solutions

https://doi.org/10.18632/oncotarget.6999
15444-15459
Abstract  |  PDF  |  Full Text  |  How to cite

Potential therapeutic implications of IL6/IL6R/gp130targeting agents in breast cancer

https://doi.org/10.18632/oncotarget.7102
15460-15473
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers

Survival benefit of radiotherapy to patients with small cell esophagus carcinoma an analysis of Surveillance Epidemiology and End Results SEER data

https://doi.org/10.18632/oncotarget.6764
15474-15480
Abstract  |  PDF  |  Full Text  |  How to cite

Regulation of androgen receptor splice variant AR3 by PCGEM1

https://doi.org/10.18632/oncotarget.7139
15481-15491
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Integrated experimental and simulation study of the response to sequential treatment with erlotinib and gemcitabine in pancreatic cancer

https://doi.org/10.18632/oncotarget.7491
15492-15506
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Isolation and characterization of renal cancer stem cells from patientderived xenografts

https://doi.org/10.18632/oncotarget.6266
15507-15524
Abstract  |  PDF  |  Full Text  |  How to cite

CD68 and interleukin 13 prospective immune markers for esophageal squamous cell carcinoma prognosis prediction

https://doi.org/10.18632/oncotarget.6900
15525-15538
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A novel intracellular antibody against the E6 oncoprotein impairs growth of human papillomavirus 16positive tumor cells in mouse models

https://doi.org/10.18632/oncotarget.6925
15539-15553
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Protective effect of αlipoic acid against radiationinduced fibrosis in mice

https://doi.org/10.18632/oncotarget.6952
15554-15565
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The prognostic value of pretreatment CA125 levels and CA125 normalization in ovarian clear cell carcinoma: a twoacademicinstitute study

https://doi.org/10.18632/oncotarget.7216
15566-15576
Abstract  |  PDF  |  Full Text  |  How to cite

Implications of a peroxisome proliferatoractivated receptor alpha PPARα ligand clofibrate in breast cancer

https://doi.org/10.18632/oncotarget.6402
15577-15599
Abstract  |  PDF  |  Full Text  |  How to cite

Metaanalysis of the association between selenium and gastric cancer risk

https://doi.org/10.18632/oncotarget.7205
15600-15605
Abstract  |  PDF  |  Full Text  |  How to cite

Sialylated immunoglobulin G can neutralize influenza virus infection through receptor mimicry

https://doi.org/10.18632/oncotarget.7244
15606-15617
Abstract  |  PDF  |  Full Text  |  How to cite

Allelespecific recognition by LILRB3 and LILRA6 of a cytokeratin 8 associated ligand on necrotic glandular epithelial cells

https://doi.org/10.18632/oncotarget.6905
15618-15631
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CCL2CCR2 axis promotes metastasis of nasopharyngeal carcinoma by activating ERK1/2MMP2/9 pathway

https://doi.org/10.18632/oncotarget.6695
15632-15647
Abstract  |  PDF  |  Full Text  |  How to cite

Integrated transcriptomic and proteomic analysis identifies protein kinase CK2 as a key signaling node in an inflammatory cytokine network in ovarian cancer cells

https://doi.org/10.18632/oncotarget.7255
15648-15661
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

BarriertoAutointegration Factor BAF involvement in prelamin Arelated chromatin organization changes

https://doi.org/10.18632/oncotarget.6697
15662-15677
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Repulsive guidance molecule B inhibits metastasis and is associated with decreased mortality in nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.7463
15678-15689
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

IMP1 suppresses breast tumor growth and metastasis through the regulation of its target mRNAs

https://doi.org/10.18632/oncotarget.7464
15690-15702
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The E1B19Kdeleted oncolytic adenovirus mutant AdΔ19K sensitizes pancreatic cancer cells to druginduced DNAdamage by downregulating Claspin and Mre11

https://doi.org/10.18632/oncotarget.7310
15703-15724
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Gamabufotalin triggers cMyc degradation via induction of WWP2 in multiple myeloma cells

https://doi.org/10.18632/oncotarget.7398
15725-15737
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Ubiquitin ligase UBE3C promotes melanoma progression by increasing epithelialmesenchymal transition in melanoma cells

https://doi.org/10.18632/oncotarget.7393
15738-15746
Abstract  |  PDF  |  Full Text  |  How to cite

Bladder cancer cells secrete while normal bladder cells express but do not secrete AGR2

https://doi.org/10.18632/oncotarget.7400
15747-15756
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genomewide functional genetic screen with the anticancer agent AMPI109 identifies PRL3 as an oncogenic driver in triplenegative breast cancers

https://doi.org/10.18632/oncotarget.7462
15757-15771
Abstract  |  PDF  |  Full Text  |  How to cite

Preneoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation

https://doi.org/10.18632/oncotarget.7513
15772-15786
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

LncRNA MT1JP functions as a tumor suppressor by interacting with TIAR to modulate the p53 pathway

https://doi.org/10.18632/oncotarget.7487
15787-15800
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Comparative efficacy and safety of firstline treatments in patients with metastatic renal cell cancer: a network metaanalysis based on phase 3 RCTs

https://doi.org/10.18632/oncotarget.7511
15801-15810
Abstract  |  PDF  |  Full Text  |  How to cite

ADPribosylation factor 1 expression regulates epithelialmesenchymal transition and predicts poor clinical outcome in triplenegative breast cancer

https://doi.org/10.18632/oncotarget.7515
15811-15827
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

High expression of RUNX1 is associated with poorer outcomes in cytogenetically normal acute myeloid leukemia

https://doi.org/10.18632/oncotarget.7489
15828-15839
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR4865p expression pattern in esophageal squamous cell carcinoma gastric cancer and its prognostic value

https://doi.org/10.18632/oncotarget.7417
15840-15853
Abstract  |  PDF  |  Full Text  |  How to cite

1433ζ promotes hepatocellular carcinoma venous metastasis by modulating hypoxiainducible factor1α

https://doi.org/10.18632/oncotarget.7493
15854-15867
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SI113 a SGK1 inhibitor potentiates the effects of radiotherapy modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells

https://doi.org/10.18632/oncotarget.7520
15868-15884
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pathway of PPARgamma coactivators in thermogenesis: a pivotal traditional Chinese medicineassociated target for individualized treatment of rheumatoid arthritis

https://doi.org/10.18632/oncotarget.7419
15885-15900
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PDL1 expression is associated with epithelialmesenchymal transition in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.7431
15901-15914
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR30e controls DNA damageinduced stress responses by modulating expression of the CDK inhibitor p21WAF1/CIP1 and caspase3

https://doi.org/10.18632/oncotarget.7432
15915-15929
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genetic variant rs4072037 of MUC1 and gastric cancer risk in an Eastern Chinese population

https://doi.org/10.18632/oncotarget.7527
15930-15936
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic significance and optimal cutoff of age in medullary thyroid cancer

https://doi.org/10.18632/oncotarget.7556
15937-15947
Abstract  |  PDF  |  Full Text  |  How to cite

A genetic variation in microRNA target site of ETS2 is associated with clinical outcomes of paclitaxelcisplatin chemotherapy in nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.7433
15948-15958
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Efficacy of targeted AKT inhibition in genetically engineered mouse models of PTENdeficient prostate cancer

https://doi.org/10.18632/oncotarget.7557
15959-15976
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Role of microRNAs in epigenetic silencing of the CHD5 tumor suppressor gene in neuroblastomas

https://doi.org/10.18632/oncotarget.7434
15977-15985
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inhibition of MARCH5 ubiquitin ligase abrogates MCL1dependent resistance to BH3 mimetics via NOXA

https://doi.org/10.18632/oncotarget.7558
15986-16002
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ZEB2 inhibits HBV transcription and replication by targeting its core promoter

https://doi.org/10.18632/oncotarget.7435
16003-16011
Abstract  |  PDF  |  Full Text  |  How to cite

Comprehensive analysis of lncRNA expression profiles and identification of functional lncRNAs in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.7559
16012-16022
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Novel role of STRAP in progression and metastasis of colorectal cancer through Wnt/βcatenin signaling

https://doi.org/10.18632/oncotarget.7532
16023-16037
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Increased expression of SUMO1P3 predicts poor prognosis and promotes tumor growth and metastasis in bladder cancer

https://doi.org/10.18632/oncotarget.6946
16038-16048
Abstract  |  PDF  |  Full Text  |  How to cite

Estrogen receptor alpha ERα/ESR1 mediates the p53independent overexpression of MDM4/MDMX and MDM2 in human breast cancer

https://doi.org/10.18632/oncotarget.7533
16049-16069
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Podoplanin is a component of extracellular vesicles that reprograms cellderived exosomal proteins and modulates lymphatic vessel formation

https://doi.org/10.18632/oncotarget.7445
16070-16089
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Involvement of SULF2 in 𝛄irradiationinduced invasion and resistance of cancer cells by inducing IL6 expression

https://doi.org/10.18632/oncotarget.7449
16090-16103
Abstract  |  PDF  |  Full Text  |  How to cite

Genetic association study identifies a functional CNV in the WWOX gene contributes to the risk of intracranial aneurysms

https://doi.org/10.18632/oncotarget.7546
16104-16111
Abstract  |  PDF  |  Full Text  |  How to cite

Cinacalcet inhibits neuroblastoma tumor growth and upregulates cancertestis antigens

https://doi.org/10.18632/oncotarget.7448
16112-16129
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

IL15 superagonist/IL15RαSushiFc fusion complex IL15SA/IL15RαSuFc; ALT803 markedly enhances specific subpopulations of NK and memory CD8+ T cells and mediates potent antitumor activity against murine breast and colon carcinomas

https://doi.org/10.18632/oncotarget.7470
16130-16145
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Soluble Tie2 overrides the heightened invasion induced by antiangiogenesis therapies in gliomas

https://doi.org/10.18632/oncotarget.7550
16146-16157
Abstract  |  PDF  |  Full Text  |  How to cite

Epigallocatechin3gallate targets cancer stemlike cells and enhances 5fluorouracil chemosensitivity in colorectal cancer

https://doi.org/10.18632/oncotarget.7567
16158-16171
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genetic mutations associated with metastatic clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.7473
16172-16179
Abstract  |  PDF  |  Full Text  |  How to cite

Loss of large tumor suppressor 1 promotes growth and metastasis of gastric cancer cells through upregulation of the YAP signaling

https://doi.org/10.18632/oncotarget.7568
16180-16193
Abstract  |  PDF  |  Full Text  |  How to cite

Tongxinluo mitigates atherogenesis by regulating angiogenic factors and inhibiting vasa vasorum neovascularization in apolipoprotein Edeficient mice

https://doi.org/10.18632/oncotarget.7477
16194-16204
Abstract  |  PDF  |  Full Text  |  How to cite

miR124 downregulation leads to breast cancer progression via LncRNAMALAT1 regulation and CDK4/E2F1 signal activation

https://doi.org/10.18632/oncotarget.7578
16205-16216
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Ribosomal protein L4 is a novel regulator of the MDM2p53 loop

https://doi.org/10.18632/oncotarget.7479
16217-16226
Abstract  |  PDF  |  Full Text  |  How to cite

Mechanosensitive caveolin1 activationinduced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility invadopodia formation and metastasis in vivo

https://doi.org/10.18632/oncotarget.7583
16227-16247
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Bromodomaincontaining protein 7 BRD7 as a potential tumor suppressor in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.7637
16248-16261
Abstract  |  PDF  |  Full Text  |  How to cite

Elevated autocrine chemokine ligand 18 expression promotes oral cancer cell growth and invasion via Akt activation

https://doi.org/10.18632/oncotarget.7585
16262-16272
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hepatocyte growth factor reduces sensitivity to the epidermal growth factor receptortyrosine kinase inhibitor gefitinib in lung adenocarcinoma cells harboring wildtype EGFR

https://doi.org/10.18632/oncotarget.7586
16273-16281
Abstract  |  PDF  |  Full Text  |  How to cite

A small molecule induces integrin β4 nuclear translocation and apoptosis selectively in cancer cells with high expression of integrin β4

https://doi.org/10.18632/oncotarget.7646
16282-16296
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ANXA11 regulates the tumorigenesis lymph node metastasis and 5fluorouracil sensitivity of murine hepatocarcinoma HcaP cells by targeting cJun

https://doi.org/10.18632/oncotarget.7484
16297-16310
Abstract  |  PDF  |  Full Text  |  How to cite

Anticancer drug 33′diindolylmethane activates Wnt4 signaling to enhance gastric cancer cell stemness and tumorigenesis

https://doi.org/10.18632/oncotarget.7684
16311-16324
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cyclic AMP responsive elementbinding protein promotes renal cell carcinoma proliferation probably via the expression of spindle and kinetochoreassociated protein 2

https://doi.org/10.18632/oncotarget.7017
16325-16337
Abstract  |  PDF  |  Full Text  |  How to cite

Serum protein profiling using an aptamer array predicts clinical outcomes of stage IIA colon cancer: A leaveoneout crossvalidation

https://doi.org/10.18632/oncotarget.7488
16338-16348
Abstract  |  PDF  |  Full Text  |  How to cite

AMPKmediated upregulation of mTORC2 and MCL1 compromises the anticancer effects of aspirin

https://doi.org/10.18632/oncotarget.7648
16349-16361
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of serologic biomarkers for predicting microvascular invasion in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.7649
16362-16371
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

EpsteinBarr virus glycoprotein gH/gL antibodies complement IgAviral capsid antigen for diagnosis of nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.7688
16372-16383
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Detection of ATRX and IDH1R132H immunohistochemistry in the progression of 211 paired gliomas

https://doi.org/10.18632/oncotarget.7650
16384-16395
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA199a and 214 as potential therapeutic targets in pancreatic stellate cells in pancreatic tumor

https://doi.org/10.18632/oncotarget.7651
16396-16408
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

microRNA206 impairs cMycdriven cancer in a synthetic lethal manner by directly inhibiting MAP3K13

https://doi.org/10.18632/oncotarget.7653
16409-16419
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prospective evaluation of 64 serum autoantibodies as biomarkers for early detection of colorectal cancer in a true screening setting

https://doi.org/10.18632/oncotarget.7500
16420-16432
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epigenetic inactivation of follistatinlike 1 mediates tumor immune evasion in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.7654
16433-16444
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

VEGFR2 targeted antibody fused with MICA stimulates NKG2D mediated immunosurveillance and exhibits potent antitumor activity against breast cancer

https://doi.org/10.18632/oncotarget.7501
16445-16461
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA30a increases tight junction protein expression to suppress the epithelialmesenchymal transition and metastasis by targeting Slug in breast cancer

https://doi.org/10.18632/oncotarget.7656
16462-16478
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A cancerfavoring oncolytic vaccinia virus shows enhanced suppression of stemcell like colon cancer

https://doi.org/10.18632/oncotarget.7660
16479-16489
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mapping of deletion breakpoints at the CDKN2A locus in melanoma: detection of MTAPANRIL fusion transcripts

https://doi.org/10.18632/oncotarget.7503
16490-16504
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Aberrant expression of nuclear HDAC3 and cytoplasmic CDH1 predict a poor prognosis for patients with pancreatic cancer

https://doi.org/10.18632/oncotarget.7663
16505-16516
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Carfilzomib potentiates CUDC101induced apoptosis in anaplastic thyroid cancer

https://doi.org/10.18632/oncotarget.7760
16517-16528
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Aquaporin 3 promotes the stemlike properties of gastric cancer cells via Wnt/GSK3β/βcatenin pathway

https://doi.org/10.18632/oncotarget.7664
16529-16541
Abstract  |  PDF  |  Full Text  |  How to cite

Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevitydefining cellular processes

https://doi.org/10.18632/oncotarget.7665
16542-16566
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR1555p inhibition promotes the transition of bone marrow mesenchymal stem cells to gastric cancer tissue derived MSClike cells via NFκB p65 activation

https://doi.org/10.18632/oncotarget.7767
16567-16580
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Preclinical activity of selinexor an inhibitor of XPO1 in sarcoma

https://doi.org/10.18632/oncotarget.7667
16581-16592
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Selective killing of gastric cancer cells by a small molecule via targeting TrxR1 and ROSmediated ER stress activation

https://doi.org/10.18632/oncotarget.7565
16593-16609
Abstract  |  PDF  |  Full Text  |  How to cite

Time trends of neonatal mortality by causes of death in Shenyang 1997–2014

https://doi.org/10.18632/oncotarget.7670
16610-16618
Abstract  |  PDF  |  Full Text  |  How to cite

FOXM1 regulates expression of eukaryotic elongation factor 2 kinase and promotes proliferation invasion and tumorgenesis of human triple negative breast cancer cells

https://doi.org/10.18632/oncotarget.7672
16619-16635
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

p85α promotes nucleolin transcription and subsequently enhances EGFR mRNA stability and EGFinduced malignant cellular transformation

https://doi.org/10.18632/oncotarget.7674
16636-16649
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The targeted histone deacetylase inhibitor tefinostat CHR2845 shows selective in vitro efficacy in monocytoidlineage leukaemias

https://doi.org/10.18632/oncotarget.7692
16650-16662
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors SKi or ABC294640 induces growth arrest in androgenindependent LNCaPAI prostate cancer cells

https://doi.org/10.18632/oncotarget.7693
16663-16675
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR1293p controls centrosome number in metastatic prostate cancer cells by repressing CP110

https://doi.org/10.18632/oncotarget.7572
16676-16687
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

APE1mediated DNA damage repair provides survival advantage for esophageal adenocarcinoma cells in response to acidic bile salts

https://doi.org/10.18632/oncotarget.7696
16688-16702
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR6523p is upregulated in nonsmall cell lung cancer and promotes proliferation and metastasis by directly targeting Lgl1

https://doi.org/10.18632/oncotarget.7697
16703-16715
Abstract  |  PDF  |  Full Text  |  How to cite

Radiation exposure young age and female gender are associated with high prevalence of RET/PTC1 and RET/PTC3 in papillary thyroid cancer: a metaanalysis

https://doi.org/10.18632/oncotarget.7574
16716-16730
Abstract  |  PDF  |  Full Text  |  How to cite

Preferential targeting of cancer stem cells in the radiosensitizing effect of ABT737 on HNSCC

https://doi.org/10.18632/oncotarget.7744
16731-16744
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Significance of the NOR1FOXA1/HDAC2Slug regulatory network in epithelialmesenchymal transition of tumor cells

https://doi.org/10.18632/oncotarget.7778
16745-16759
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Heterogeneous nuclear ribonucleoproteins A1 and A2 modulate expression of Tid1 isoforms and EGFR signaling in nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.7606
16760-16772
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Development of a specific affinitymatured exosite inhibitor to MT1MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo

https://doi.org/10.18632/oncotarget.7780
16773-16792
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

hnRNP A1mediated translational regulation of the G quadruplexcontaining RON receptor tyrosine kinase mRNA linked to tumor progression

https://doi.org/10.18632/oncotarget.7589
16793-16805
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cigarette smoking complements the prognostic value of baseline plasma EpsteinBarr virus deoxyribonucleic acid in patients with nasopharyngeal carcinoma undergoing intensitymodulated radiation therapy: a largescale retrospective cohort study

https://doi.org/10.18632/oncotarget.7609
16806-16817
Abstract  |  PDF  |  Full Text  |  How to cite

Interaction of antihistaminic drugs with human translationally controlled tumor protein TCTP as novel approach for differentiation therapy

https://doi.org/10.18632/oncotarget.7605
16818-16839
Abstract  |  PDF  |  Full Text  |  How to cite

Thymic stromal lymphopoietin TSLP inhibits human colon tumor growth by promoting apoptosis of tumor cells

https://doi.org/10.18632/oncotarget.7614
16840-16854
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Exceptional antineoplastic activity of a dendriticcelltargeted vaccine loaded with a Listeria peptide proposed against metastatic melanoma

https://doi.org/10.18632/oncotarget.7806
16855-16865
Abstract  |  PDF  |  Full Text  |  How to cite

STIM1 plays an important role in TGFβinduced suppression of breast cancer cell proliferation

https://doi.org/10.18632/oncotarget.7619
16866-16878
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Areca nut components stimulate ADAM17 IL1α PGE2 and 8isoprostane production in oral keratinocyte: role of reactive oxygen species EGF and JAK signaling

https://doi.org/10.18632/oncotarget.7621
16879-16894
Abstract  |  PDF  |  Full Text  |  How to cite

iACP: a sequencebased tool for identifying anticancer peptides

https://doi.org/10.18632/oncotarget.7815
16895-16909
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ISG15 predicts poor prognosis and promotes cancer stem cell phenotype in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.7626
16910-16922
Abstract  |  PDF  |  Full Text  |  How to cite

Diagnostic and prognostic relevance of circulating exosomal miR373 miR200a miR200b and miR200c in patients with epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.7850
16923-16935
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ROCK1 via LIM kinase regulates growth maturation and actin based functions in mast cells

https://doi.org/10.18632/oncotarget.7851
16936-16947
Abstract  |  PDF  |  Full Text  |  How to cite

Comparative analysis of tumor spheroid generation techniques for differential in vitro drug toxicity

https://doi.org/10.18632/oncotarget.7659
16948-16961
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

High throughput microscopy identifies bisphenol AP a bisphenol A analog as a novel AR downregulator

https://doi.org/10.18632/oncotarget.7655
16962-16974
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lymph nodes regression grade is a predictive marker for rectal cancer after neoadjuvant therapy and radical surgery

https://doi.org/10.18632/oncotarget.7703
16975-16984
Abstract  |  PDF  |  Full Text  |  How to cite

Tumorassociated antigen CAPERα and microvessel density in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.7707
16985-16995
Abstract  |  PDF  |  Full Text  |  How to cite

Cholesterol consumption and risk of endometrial cancer: a systematic review and doseresponse metaanalysis of observational studies

https://doi.org/10.18632/oncotarget.7913
16996-17008
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Oroxylin A modulates mitochondrial function and apoptosis in human colon cancer cells by inducing mitochondrial translocation of wildtype p53

https://doi.org/10.18632/oncotarget.7927
17009-17020
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Chronic inflammation contributes to the development of hepatocellular carcinoma by decreasing miR122 levels

https://doi.org/10.18632/oncotarget.7740
17021-17034
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Intravenous administration of the selective tolllike receptor 7 agonist DSR29133 leads to antitumor efficacy in murine solid tumor models which can be potentiated by combination with fractionated radiotherapy

https://doi.org/10.18632/oncotarget.7928
17035-17046
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

KU0060648 inhibits hepatocellular carcinoma cells through DNAPKcsdependent and DNAPKcsindependent mechanisms

https://doi.org/10.18632/oncotarget.7742
17047-17059
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Combination of metronomic cyclophosphamide and dietary intervention inhibits neuroblastoma growth in a CD1nu mouse model

https://doi.org/10.18632/oncotarget.7929
17060-17073
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

VEGF promotes gastric cancer development by upregulating CRMP4

https://doi.org/10.18632/oncotarget.7717
17074-17086
Abstract  |  PDF  |  Full Text  |  How to cite

Genomic characterization of patientderived xenograft models established from fine needle aspirate biopsies of a primary pancreatic ductal adenocarcinoma and from patientmatched metastatic sites

https://doi.org/10.18632/oncotarget.7718
17087-17102
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Therapy of pancreatic cancer via an EphA2 receptortargeted delivery of gemcitabine

https://doi.org/10.18632/oncotarget.7931
17103-17110
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumorpromoting function and prognostic significance of the RNAbinding protein Tcell intracellular antigen1 in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.7937
17111-17128
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

N52 monodeamidated Bcl‑xL shows impaired oncogenic properties in vivo and in vitro

https://doi.org/10.18632/oncotarget.7938
17129-17143
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MMP13 is involved in oral cancer cell metastasis

https://doi.org/10.18632/oncotarget.7942
17144-17161
Abstract  |  PDF  |  Full Text  |  How to cite

ER maleate is a novel anticancer agent in oral cancer: implications for cancer therapy

https://doi.org/10.18632/oncotarget.7751
17162-17181
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association of helicobacter pylori infection and chronic atrophic gastritis with risk of colonic pancreatic and gastric cancer: A tenyear followup of the ESTHER cohort study

https://doi.org/10.18632/oncotarget.7946
17182-17193
Abstract  |  PDF  |  Full Text  |  How to cite

Combining BRAF inhibitor and anti PDL1 antibody dramatically improves tumor regression and anti tumor immunity in an immunocompetent murine model of anaplastic thyroid cancer

https://doi.org/10.18632/oncotarget.7839
17194-17211
Abstract  |  PDF  |  Full Text  |  How to cite

TIKI2 is upregulated and plays an oncogenic role in renal cell carcinoma

https://doi.org/10.18632/oncotarget.7873
17212-17219
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Apatinib inhibits VEGF signaling and promotes apoptosis in intrahepatic cholangiocarcinoma

https://doi.org/10.18632/oncotarget.7948
17220-17229
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

Impact of cytomegalovirus reactivation on relapse and survival in patients with acute leukemia who received allogeneic hematopoietic stem cell transplantation in first remission

https://doi.org/10.18632/oncotarget.7347
17230-17241
Abstract  |  PDF  |  Full Text  |  How to cite

Combined analysis of circulating epithelial cells and serum thyroglobulin for distinguishing disease status of the patients with papillary thyroid carcinoma

https://doi.org/10.18632/oncotarget.6587
17242-17253
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MR imaging biomarkers for evaluating therapeutic effects shortly after near infrared photoimmunotherapy

https://doi.org/10.18632/oncotarget.7357
17254-17264
Abstract  |  PDF  |  Full Text  |  How to cite

Clinicopathologic distribution of KRAS and BRAF mutations in a Chinese population with colorectal cancer precursor lesions

https://doi.org/10.18632/oncotarget.7504
17265-17274
Abstract  |  PDF  |  Full Text  |  How to cite

Nomograms for predicting Gleason upgrading in a contemporary Chinese cohort receiving radical prostatectomy after extended prostate biopsy: development and internal validation

https://doi.org/10.18632/oncotarget.7787
17275-17285
Abstract  |  PDF  |  Full Text  |  How to cite


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